Longevity Protocol — Cellular Energy & Repair
Restore energy at the cellular level
NAD+ is the coenzyme your cells use for everything — energy, metabolism, DNA repair, and healthy aging. Levels drop by more than 50% between your 20s and 50s. Restoring them changes how you feel at the source.
Why NAD+
Your cells are tired. NAD+ is why they recover.
NAD+ is involved in over 400 cellular reactions. It is not a supplement trend — it is the foundational molecule your mitochondria depend on to convert food into energy, repair DNA damage, and regulate the biological clock of aging.
After 30, NAD+ levels fall steadily. By 50, most women have less than half the NAD+ they had at 20. Injectable NAD+ restores levels directly — with a bioavailability that oral supplements, sprays, and precursors simply cannot match.
Philosophy
Unhurried. Evidence-based. Yours. We treat the whole woman, not the symptom list.
Our Physicians
Board-certified women's health specialists, licensed in your state, who review every intake personally.
Your Protocol
Compounded pharmacy. Discreet delivery. More NAD+ per milligram than any comparable program.
Ongoing Care
Unlimited messaging with your care team. Monthly check-ins. Your dosing adjusts as your body responds.
The Science
NAD+ is the molecule at the center of how you age
Nicotinamide Adenine Dinucleotide (NAD+) is a coenzyme present in every living cell. It acts as a critical electron carrier in the production of ATP — the energy currency your cells run on — and activates the sirtuins and PARP enzymes responsible for DNA repair and cellular resilience.
Injectable NAD+ delivers the molecule directly into your bloodstream, bypassing the conversion losses that limit oral NMN, NR, and other precursor supplements. The result is a more immediate, more measurable restoration of cellular function.
MADRES protocols include 1,200–2,000mg per cycle — two to four times the NAD+ included in most clinical programs — compounded at 200mg/ml by 503A LegitScript-certified pharmacies.
Six Ways NAD+ Restores You
Energy, repair, and resilience — from the inside out
01
Cellular Energy Production
NAD+ is essential for mitochondrial function and ATP synthesis — the energy your cells need to power every system in your body, from muscle to brain.
02
Mental Clarity & Focus
Fuels neurons with energy, supports neurotransmitter production, and protects against neurodegenerative decline. Most women notice sharper thinking within the first two weeks.
03
DNA Repair & Longevity
Activates PARP enzymes that detect and repair DNA damage — the foundation of healthy aging, genomic stability, and long-term cellular integrity.
04
Metabolic Efficiency
Regulates glucose and lipid metabolism at the cellular level, supporting efficient energy use, fat oxidation, and overall metabolic balance as hormones shift.
05
Healthy Aging via Sirtuins
Activates sirtuin proteins that regulate cellular health, reduce chronic inflammation, and improve stress resilience — the biological drivers of slower aging.
06
Immune & Recovery Support
Fuels immune cell activity and accelerates recovery from illness, inflammation, and physical exertion. Women on NAD+ report faster bounce-back from everything.
Your Restoration Timeline
What to expect — and when
Month 1
The Lift
Clean, sustained energy without the crash. Sharper focus and improved mood within the first two weeks. Most women describe it as the fog lifting — not a stimulant feeling, but a baseline restoration.
Month 2
The Steadiness
Steadier energy throughout the day. Stronger recovery after workouts and stress. Better sleep quality and improved stress resilience as cellular repair compounds.
Month 3+
The Compound
Sustained metabolic efficiency, enhanced skin tone and texture, and long-term DNA repair support. The benefits of NAD+ build on themselves — this is where the real shift happens.
Choose Your Protocol
More NAD+ than anywhere else. Transparent pricing.
NAD+ Home Kit
1,200mg / 6ml · Standard monthly cycle
$247
Per cycle · No hidden fees, ever
NAD+ XL Home Kit
2,000mg / 10ml · Maximum dosing cycle
$327
Per cycle · No hidden fees, ever
FSA / HSA eligible. You will not be charged unless approved by a licensed physician. Ships to: AZ, CA, CO, FL, GA, IL, IN, MA, MD, MI, MO, NC, ND, NV, NY, OH, OK, OR, PA, SC, SD, TN, TX, UT, VA, WA, WY.
The Process
Simple. Private. Yours.
A thoughtful intake. A physician who listens. Your protocol, delivered — and a team that stays with you after.
Begin Your ConsultationOnline · Private · Secure
Complete your health history
A thoughtful intake designed to actually understand you. Takes 5 minutes — not a generic form. HIPAA-protected and reviewed only by your assigned physician.
Video or Async · 48hr Turnaround
Meet your MADRES physician
A board-certified doctor, licensed in your state, reviews your intake and consults with you directly. You are not charged unless approved for treatment.
Pharmacy Compounded · Discreet Delivery
Receive your protocol
Your NAD+ is compounded at a 503A certified pharmacy, packaged discreetly, and delivered overnight via FedEx or UPS — free of charge. No PO boxes.
Unlimited Messaging · Monthly Check-ins
Ongoing care, not a one-time script
Your MADRES team checks in regularly. Adjust dosing, refine your protocol, and evolve your approach as your body responds. This is a relationship — not a transaction.
Pharmacy Quality & Safety
Every batch tested before it ships
✓ Potency Test — Passed
Active Ingredient Verified
Performed multiple times per week. Confirms the medication contains the correct concentration of NAD+ within plus or minus 10% as required by law — results are typically within 2%.
✓ Sterility Test — Passed
Contaminant Free
Every batch is tested to confirm the medication is free from bacteria and other pathogens, meeting all requirements of USP 797 compounding standards.
✓ pH Test — Passed
Injection Comfort Assured
Assesses acid/base balance to ensure minimal irritation upon subcutaneous injection. MADRES partners only with pharmacies that test every batch — not every batch type.
✓ Purity Test — Passed
Endotoxin Free
Every batch is tested for bacterial endotoxins per USP 85 standards. MADRES partners exclusively with 503A LegitScript-certified pharmacies — the highest compounding certification available.
From the MADRES Community
Women who chose to restore
"Within two weeks I noticed something shifted. Not wired — just clear. Like my brain finally had the fuel it needed. I hadn't felt that way in years."
Adriana S.
Age 46 · On protocol 3 months
"I do NAD+ and Sermorelin together. The combination is unlike anything I've tried. My energy is consistent, my recovery is faster, and my skin looks genuinely different."
Melissa T.
Age 39 · Combined protocol
"I was skeptical about injections but the instructions made it easy. Month two I started sleeping through the night for the first time in years. I didn't expect that at all."
Renee P.
Age 52 · On protocol 5 months
Safety & Medical Context
Informed decisions, supported by physicians
Why injectable NAD+ vs. oral supplements
Injectable NAD+ delivers the molecule directly into your bloodstream — bypassing the conversion losses that limit NMN, NR, and other oral precursors. At-home subcutaneous injections provide the same bioavailability as IV infusions at a fraction of the cost and time, with flexible dosing throughout the week to maximize cellular uptake.
Who should not use NAD+
Not appropriate for individuals who are pregnant or breastfeeding, have active cancer, or have a severe heart condition such as coronary artery disease or a history of heart attack. Those with high blood pressure or anxiety disorders should begin at the minimum dose and titrate slowly. Your intake form captures this for physician review.
Common side effects
NAD+ is generally well-tolerated — it is a bioidentical molecule your body already produces. Most side effects are dose-dependent and subside within 2–12 hours:
- Flushing or warm sensation post-injection
- Mild nausea or headache
- Temporary fatigue or drowsiness
- Injection site redness or swelling
- Rarely: mild chest tightness or feelings of restlessness
Medications & supplements to avoid
Do not take additional NAD+ via IV infusion or other injectable means alongside this protocol. Do not take NMN or NR supplements concurrently — they compete with the same pathways. NAD+ topical creams and lotions are safe to use alongside injectable NAD+. Always inform your MADRES physician of all current supplements and medications.
Common Questions
Answered by our clinical team
Begin Your Protocol
Every cell in your body is waiting for this.
NAD+ doesn't force energy — it restores the conditions your cells need to create their own. Pre-qualify in 60 seconds.
Pre-Qualify Now© 2026 MADRES Health LLC. All prescription protocols require review by an independent licensed provider. Compounded medications are not FDA-reviewed for safety or efficacy. Statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. Always consult a healthcare provider before making medical decisions.